| Inter Miami CF vs. CF Montreal |
May 12, 2021
Wed TBA |
DRV PNK Stadium Fort Lauderdale, FL |
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| Toronto FC vs. Columbus Crew SC |
May 12, 2021
Wed 7:00PM |
Exploria Stadium Orlando, FL |
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| Minnesota United FC vs. Vancouver Whitecaps FC |
May 12, 2021
Wed 7:00PM |
Allianz Field Saint Paul, MN |
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| Philadelphia Union vs. New England Revolution |
May 12, 2021
Wed 7:30PM |
Subaru Park Chester, PA |
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| Sacramento Republic FC vs. Las Vegas Lights FC |
May 12, 2021
Wed 7:30PM |
Heart Health Park Sacramento, CA |
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| San Jose Earthquakes vs. Seattle Sounders FC |
May 12, 2021
Wed 7:30PM |
PayPal Park San Jose, CA |
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| Houston Dynamo vs. Sporting Kansas City |
May 12, 2021
Wed 7:30PM |
BBVA Stadium Houston, TX |
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| D.C. United vs. Chicago Fire |
May 13, 2021
Thu 8:00PM |
Audi Field Washington, DC |
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| New York Red Bulls II vs. Miami FC |
May 14, 2021
Fri 7:00PM |
Montclair State University Montclair, NJ |
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| Real Monarchs SLC vs. LA Galaxy II |
May 14, 2021
Fri 7:00PM |
Zions Bank Stadium Herriman, UT |
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| LA Galaxy vs. Austin FC |
May 15, 2021
Sat 12:30PM |
Dignity Health Sports Park - Stadium Carson, CA |
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| New York City FC vs. Toronto FC |
May 15, 2021
Sat 3:00PM |
Yankee Stadium Bronx, NY |
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| Racing Louisville FC vs. FC Kansas City |
May 15, 2021
Sat 5:00PM |
Lynn Family Stadium Louisville, KY |
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| NJ/NY Gotham FC vs. Houston Dash |
May 15, 2021
Sat 7:00PM |
Red Bull Arena - NJ Harrison, NJ |
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| Atlanta United FC vs. CF Montreal |
May 15, 2021
Sat 7:00PM |
Mercedes-Benz Stadium Atlanta, GA |
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| Colorado Rapids vs. Houston Dynamo |
May 15, 2021
Sat 7:00PM |
Dick's Sporting Goods Park Commerce City, CO |
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| Minnesota United FC vs. FC Dallas |
May 15, 2021
Sat 7:00PM |
Allianz Field Saint Paul, MN |
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| San Jose Earthquakes vs. Portland Timbers |
May 15, 2021
Sat 7:00PM |
PayPal Park San Jose, CA |
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| New Mexico United vs. Austin Bold FC |
May 15, 2021
Sat 7:30PM |
Rio Grande Credit Union Field at Isotopes Park Albuquerque, NM |
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| Philadelphia Union vs. New York Red Bulls |
May 15, 2021
Sat 7:30PM |
Subaru Park Chester, PA |
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| Flint City Bucks vs. Toledo Villa FC |
May 15, 2021
Sat 7:30PM |
Atwood Stadium Flint, MI |
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| Real Salt Lake vs. Nashville SC |
May 15, 2021
Sat 7:30PM |
Rio Tinto Stadium Sandy, UT |
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| Sporting Kansas City vs. Vancouver Whitecaps FC |
May 16, 2021
Sun 1:00PM |
Children's Mercy Park Kansas City, KS |
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| Portland Thorns FC vs. Chicago Red Stars |
May 16, 2021
Sun 4:00PM |
Providence Park Portland, OR |
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| New England Revolution vs. Columbus Crew SC |
May 16, 2021
Sun 6:00PM |
Gillette Stadium Foxborough, MA |
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